Cubically
Cubically was created in 2017 by me, MD XF. It is built around the main piece of memory, a Rubik's Cube. To my knowledge there were (and are) no existing languages with a similar design.
The memory cube begins with this initialization:
000 (top face)
000
000
111222333444 (left, front, right, and back faces, respectively)
111222333444
111222333444
555 (bottom face)
555
555
Each integer represents a cubelet. After performing a 90° clockwise right turn (R1